Abstract: According to the rich nutrition ingredient and anti-insect pest ingredient included in anaerobic fermentation slurry and the physiology biochemical characteristics of the aphides, the authors choose various pesticidal antibiotic and lixiviated liquid which can strengthen the ability of crops to resist diseases, suppress the pathogen to grow, cause the wall cells of the aphides to be poisoned and body function to be disordered to make different kinds of compound additives. Then experimental research on the result of the compound pesticide for killing aphides was carried out, the mechanism and effect of the compound pesticide were preliminarily discussed, in order to provide scientific reference for researching and developing secure living pesticide which can replace the chemical pesticide, using anaerobic fermentation slurry as main raw materials. Finally it indicates that five kinds of the compound pesticide selected in this text are able to obviously enhance the effect of killing aphides. It shows that the respective volume ratio between the anaerobic fermentation slurry and the additives BP01 is 8000～11000, BP02 is 25000～30000, BP03 is 8333～12500, BP04 is 18000 ～25000, BP05 is 10000～15000.